|
> Wissenschaftliche Publikationen <
|
Retrospective neuropathological review of prion disease in UK haemophilic patients. Thrombosis and Haemostasis 80, 909-911.
| Lee C.A., Ironside, James W., Bell, Jeanne E., Giangrande, Paul, Ludlam, Christopher, Esiri, Margaret M., McLaughlin, James E. (1998).
| In 1996, the CJD surveillance unit in Edinburgh, UK described nvCJD which was thought to be the human equivalent of bovine spongiform encephalopathy (BSE). The identification of prion protein in the tonsil of an affected individual has raised the question of transmission of nvCJD via blood products. This study examines the post mortem brains of 33 patients who were treated with clotting factor concentrate of predominately UK donor source during the years 1962-1995. The brains were examined by conventional histological methods and also for the prion protein using monoclonal antibodies KG9 and 3F4. No evidence of spongiform encephalopathy was found and the immunocytochemistry was negative for PrP in all cases. It is concluded that, at present, there is no evidence for the transmission of nvCJD via clotting factor concentrate to patients with haemophilia.
| | Zurück |
|
|
Interviews mit Forschern
Erfahren Sie mehr über einzelne Forschungsprojekte und die Leute, die dahinterstehen. | 
Gentechnik im Klassenzimmer
Aufgaben zum Thema Gentechnik, die in den Schulunterricht integriert werden können. | 
Genomik und Proteomik
Wie man heute die Gene und Proteine eines Organismus untersucht. | 
Forschungseinblicke
Verfolgen Sie die Arbeit an aktuellen Projekten, z.B. am Weizen, Fadenwurm oder in der Krebsforschung. |
|
