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The feeding value of soybeans fed to rats, chickens, catfish and dairy cattle is not altered by genetic incorporation of glyphosate tolerance. Journal of Nutrition 126, 717-727.
Hammond B.G., Vicini, John L., Hartnell, Gary F., Naylor, Mark W., Knight, Christopher D., Robinson, Edwin H., Fuchs, Roy L., Padgette, Stephen R. (1996).
Animal feeding studies were conducted with rats, broiler chickens, catfish and dairy cows as part of a safety assessment program for a soybean variety genetically modified to tolerate in-season application of glyphosate. These studies were designed to compare the feeding value (wholesomeness) of two lines of glyphosate-tolerant soybeans (GTS) to the feeding value of the parental cultivar from which they were derived. Processed GTS meal was incorporated into the diets at the same concentrations as used commercially; dairy cows were fed 10 g/100 g cracked soybeans in the diet, a level that is on the high end of what is normally fed commercially. In a separate study, laboratory rats were fed 5 and 10 g unprocessed soybean meal 100 g diet. The study durations were 4 wk (rats and dairy cows), 6 wk (broilers) and 10 wk (catfish). Growth, feed conversion (rats, catfish, broilers), fillet composition (catfish), and breast muscle and fat pad weights (broilers) were compared for animals fed the parental and GTS lines. Milk production, milk composition, rumen fermentation and nitrogen digestibility were also compared for dairy cows. In all studies, measured variables were similar for animals fed both GTS lines and the parental line, indicating that the feeding value of the two GTS lines is comparable to that of the parental line. These studies support detailed compositional analysis of the GTS seeds, which showed no meaningful differences between the parental and GTS lines in the concentrations of important nutrients and antinutrients. They also confirmed the results of other studies that demonstrated the safety of the introduced protein, a bacterial 5-enolpyruvyl-shikimate-3-phosphate synthase from Agrobacterium sp. strain CP4.
The feeding value of two lines of glyphosate-tolerant soybeans were compared to the feeding value of the parental cultivar from which they were derived. The study durations were 4 weeks for rats and dairy cows, 6 weeks for broilers and 10 weeks for catfish. Growth and feed conversion were measured for rats, catfish and broilers, fillet composition was measured in catfish and breast muscle and fat pad weight were monitored in broilers, comparing animals fed with the parental and the transgenic lines. Milk production and composition, rumen fermentation and nitrogen digestability were compared for dairy cows. All measured values were similar whether animals were fed the transgenic or the parental line, indicatin that the feeding value of the two transgenic lines is comparable to the parental lines.
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